Rebellious Qi of the Chong Mai is a relatively common pathology; it is more common in women than men. In women, I have seen at all ages, from teenagers to women over 65. The first mention of Rebellious Qi of the Chong Mai is in chapter 29 of the Nan Jing: “The pathology of the Chong Mai is rebellious Qi with internal urgency [li ji].”
Li Shi Zhen says the same thing: “When Qi rebels upwards, there is internal urgency [li ji] and a feeling of heat: this is rebellious Qi of the Chong Mai.”
By Pöllö (Own work) [CC BY 3.0 (http://creativecommons.org/licenses/by/3.0)], via Wikimedia Commons