As with any number of the fMRI studies done with acupuncture, needling the point activated a number of areas in the brain. The researchers, however, did notice a difference in responses between genders – “relative to males, females exhibited greater brain activation in the right-sided postcentral gyrus, precentral gyrus, precuneus, postcentral gyrus, inferior parietal lobule, declive, middle occipital gyrus and parahippocampal gyrus”.